“Paraxanthine is a down-stream metabolite of caffeine… It’s a very interesting ingredient. People report to being optimized and not being stimulated,” said Shawn Wells, who co-founded Ingenious Ingredients (ING2) in 2018 with Ralf Jaeger, Martin Purpura, and Kylin Liao.
“We’re not competing against any ingredients. This is caffeine-evolved. It’s a $1 trillion market,” Wells told NutraIngredients-USA at the recent SupplySide West show.
Slow vs fast caffeine metabolizers
Wells explained that about one third of the population are fast metabolizers of caffeine: These are the people who can go straight to sleep after they have a cup of coffee. On the other hand, about a third of the population are slow metabolizers, and have problems with issues like headaches and arrhythmia: All the side effects and very little benefits.
“We are researching why this is the case, but one of the reasons we think this is that caffeine exerts physiological effects in of itself, especially for slow metabolizers,” he explained. “Caffeine does metabolize into paraxanthine, as well as theobromine and theophylline, but we’re seeing that caffeine has greater toxicity, theophylline has greater toxicity and more side effects. But people who experience the benefits of caffeine, which is a small segment, what we’re seeing is that it’s converting into the metabolite paraxanthine.”
The company is branding the ingredient Infinite, but it’s pronounced infinity.
“What we’re also seeing is that [paraxanthine] is more dopaminergic, which is really cool,” he said. “This means that, one, it’s neuroprotective, and, two, it means you have greater focus and performance enhancement when it comes to athletic activity and endurance, etc.”
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'This is caffeine-evolved': Ingenious Ingredients co-founder talks up potential of paraxanthine - NutraIngredients-usa.com
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